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HOME > Functional Assays > Membrane Potential
Oxonol V
   
ÄÚ    µå : 21416
´Ü     À§ : 25 mg
°ø ±Þ ¿ø : ABD Bioquest
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  Oxonol V
Oxonol V [Bis-(3-phenyl-5-oxoisoxazol-4-yl)pentamethine oxonol]


Storage : 4¡É
Ex (nm) / Em (nm) : 610 / 639
Solvent : DMSO

Molecular Formula   : C23H16N2O4
Molecular Weight     : 384.39
CAS Number/Name : 61389-30-8 / 5(4H)-Isoxazolone, 4-(5-(5-hydroxy-3-phenyl-4-isoxazolyl)-2,4-pentadienylidene) -3-phenyl


Oxonol V is a sensitive slow-response membrane potential probe that is widely used for measuring membrane potentials of many biological systems. The fluorescence of Oxonol V decreases upon membrane hyperpolarization. In general, slow-response probes exhibit potential-dependent changes in their transmembrane distribution that are accompanied by a fluorescence change. The magnitude of their optical responses is much larger than that of fast-response probes (typically a 1% fluorescence change per mV). Slow-response probes, which include cationic carbocyanines, rhodamines and anionic oxonols, are suitable for detecting changes in average membrane potentials of nonexcitable cells caused by respiratory activity, ion-channel permeability, drug binding and other factors.
   
 
  ion_channel

Product Code

Unit

Price

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21416

25 mg