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HOME > Functional Assays > Calcium Detection
Calbryte™ 520 AM
   
코    드 : 20651
단     위 : 10x50 ug
공 급 원 : AAT bioquest
가     격 : 문의
 
       
   
       
 
  Calbryte 520 AM
Calbryte™ 520 AM


Ex/Em (nm)      492/514
MW                  1090.90
CAS #               N/A
Solvent             DMSO
Storage            -15℃,  F/D/L


Calbryte™ 520, AM is a new fluorescent and cell-permeable calcium indicator. Like other dye AM cell loading, Calbryte™ 520 AM ester is non-fluorescent and once gets inside cells, it is hydrolyzed by intracellular esterase and gets activated. The activated indicator is a polar molecule that is no longer capable of freely diffusing through cell membrane, essentially trapped inside cells. Upon binding Ca2+ ions, Calbryte™ 520 produces bright fluorescence signal with extremely high signal/background ratio. In addition, Calbryte™ 520 demonstrates greatly improved intracellular retention. It has the identical excitation and emission wavelength as Fluo-4, thus the same Fluo-4 assay settings can be readily applied to Calbryte™ 520-based calcium assays. Calbryte™ 520 is a new generation of fluorescent indicators for the measurement of intracellular calcium. Its greatly improved signal/background ratio and intracellular retention properties make Calbryte™ 520 AM the most robust indicator for evaluating GPCR and calcium channel targets as well as for screening their agonists and antagonists in live cells.
   
 
  >Calbryte 520 AM

Product Code

Unit

Price

Availability

20650

2x50 ug

20651

10x50 ug

20653

1 mg

20656

2x50 ug

20658

10x50 ug